RESEARCH ATLASRESEARCH > HYPE
PUBLIC RESEARCH EDITION
Neuro / reproductive

Kisspeptin

KISS1 receptor → GnRH → LH / FSH · Peptide

Evidence at a glance

Each record keeps its own evidence class. Counts are records in this public edition, not a quality score.

Evidence gap: Route-specific human PK and absolute bioavailability are not established in the imported material.

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Records (3)

H

Human clinical / research

Human clinical / research

Human reproductive-axis research

Human studies use indication-specific IV or SC administration.

Context: Imported field-guide summary; primary citation incomplete.

Limitations: No universal testosterone-support protocol; specific primary trial not supplied.

Route: IV / SC

  • Peptide Protocol Field Guide · version 7
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Human clinical / research

Indication-specific IV / SC research pattern

Distinct protocol, timing or sequence preserved from the saved research material. Unreported fields remain unknown.

Context: Human

Human study regimen: Route: IV / SC; Species: Human

Limitations: No trial-specific amount, schedule, formulation or duration is supplied. No universal testosterone-support protocol is established.

Route: IV / SC

  • Peptide Protocol Field Guide · version 7
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U

Unresolved / evidence gap

Unresolved / evidence gap

Kisspeptin in human reproduction: KNDy neuron review (Endocr J 2024)

A 2024 review reports that peripheral kisspeptin raises gonadotropins in humans; twice-daily subcutaneous kisspeptin-54 in hypothalamic amenorrhoea increased LH pulses but lost effect within 14 days through receptor desensitization; and an intravenous kisspeptin-10 test helped predict progression in delayed puberty.

Context: Narrative review of human studies.

Limitations: Review; doses and study sizes not given; summarizes cited human studies.

Route: SC (kisspeptin-54), IV (kisspeptin-10)

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Educational research summary. Study amounts are research context, not a dose recommendation. Not medical advice.