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PUBLIC RESEARCH EDITION
Metabolic / appetite

O304 / ATX-304 research

Pan-AMPK activation · Small molecule
Also known as ATX304 O-304

Evidence at a glance

Each record keeps its own evidence class. Counts are records in this public edition, not a quality score.

Evidence gap: Route-specific human PK and absolute bioavailability are not established in the imported material.

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Records (4)

H

Human clinical / research

Human clinical / research

Short oral TELLUS study

Human oral administration and exposure are documented for the studied O304 formulation.

Context: 65 adults with type 2 diabetes taking metformin.

Limitations: No retail-capsule equivalence, long-term safety, or SLU sequencing benefit is established.

Route: Oral · Absolute human bioavailability percentage is not established here.

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Human clinical / research

TELLUS study regimen

Distinct protocol, timing or sequence preserved from the saved research material. Unreported fields remain unknown.

Context: Human · 65 adults with type 2 diabetes on metformin · O304 oral suspension

Human study regimen: Amount: 1,000 mg; Frequency: Daily; Duration: 28 days; Route: Oral; Species: Human; Population: 65 adults with type 2 diabetes on metformin; Formulation: O304 oral suspension

Limitations: Do not infer retail ATX-304 capsule equivalence, long-term safety or benefit after SLU-PP-332.

Route: Oral

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A

Anecdote / history

Anecdote / history

Jones O304 introduction / overlap option

Distinct protocol, timing or sequence preserved from the saved research material. Unreported fields remain unknown.

Context: Attributed research context; population or formulation not fully specified.

Attributed proposal / anecdote: Route: Oral; Sequence: After a proposed SLU-PP-332 reset and increased calorie intake; overlap also permitted by speaker

Limitations: No dose, frequency, duration or phase interval is given. TELLUS dosing does not supply the video’s missing protocol.

Route: Oral

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U

Unresolved / evidence gap

Unresolved / evidence gap

Identity and newer-development limits

Verify exact identity and formulation before assigning O304 findings to an ATX-304 product.

Context: A 2026 phase 1b abstract was noted but full results were inaccessible.

Limitations: The older trial is not the whole development record; unknown is not zero exposure.

Route: Not documented

  • Peptide Protocol Field Guide · version 7
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Educational research summary. Study amounts are research context, not a dose recommendation. Not medical advice.